Thursday, June 9, 2011

Q: Which commonly use ICU vasopressor is also used as a treatment to abort low flow priapism?

Answer: Phenyepherine

Phenylephrine is also used to abort priapism. It is diluted and injected directly into the corpora cavernosa. The mechanism of action is to cause constriction of the blood vessels entering into the penile region thus breaking the cycle that continues the priapism. Dose: Mixture of 1 ampule of phenylephrine (1 mL:1000 mcg) and dilute it with an 9 mL of normal saline. Use a 29-gauge needle, inject 0.3-0.5 mL into the corpora cavernosa, wait 10-15 minutes before repeating the dose.

Other pressor which can also be used is epinephrine. Methylene blue is also been suggested for the same pupose.